Summary: Recent advances in synthetic embryology have opened new avenues for understanding the complex events controlling mammalian peri-implantation development.Here, we show that mouse embryonic stem cells (ESCs) solely exposed to chemical inhibition of SUMOylation generate embryo-like structures comprising anterior neural and trunk-associated re
Abstract Background Housing environments shape injection drug-related risks and harms and thus represent a critical implementation setting for syringe services programs (SSPs).As critical harm reduction measures, SSPs sweatshirts provide safe injecting equipment to people who inject drugs (PWID).Vancouver, Canada, has well-established syringe distr
The mechanisms involved in the homogeneous perception of odorant mixtures remain largely unknown.With the aim of enhancing knowledge about blending and masking mixture perceptions, we focused on structure-odor relationships by combining the classification and pharmacophore approaches.We built a dataset of about 5000 molecules and their related odor